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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDS5B
All Species:
31.52
Human Site:
S758
Identified Species:
57.78
UniProt:
Q9NTI5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTI5
NP_055847.1
1447
164667
S758
L
H
K
S
L
D
P
S
N
L
E
H
L
I
T
Chimpanzee
Pan troglodytes
XP_509623
1487
169149
S798
L
H
K
S
L
D
P
S
N
L
E
H
L
I
T
Rhesus Macaque
Macaca mulatta
XP_001118201
1528
173307
S838
L
H
K
S
L
D
P
S
N
L
E
H
L
I
T
Dog
Lupus familis
XP_543139
1623
183240
S933
L
H
K
S
L
D
P
S
N
L
E
H
L
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q4VA53
1446
164401
S758
L
H
K
S
L
D
P
S
N
L
E
H
L
I
T
Rat
Rattus norvegicus
Q6TRW4
1447
164441
S758
L
H
K
S
L
D
P
S
N
L
E
H
L
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509617
1452
165101
S758
L
H
K
S
L
D
P
S
N
L
E
H
L
I
T
Chicken
Gallus gallus
Q5F3U9
1412
161007
S758
L
H
K
S
L
D
P
S
N
F
E
H
L
I
T
Frog
Xenopus laevis
Q5U241
1464
166906
G758
L
H
K
S
L
D
P
G
N
P
E
Q
L
I
T
Zebra Danio
Brachydanio rerio
A1L1F4
1320
148940
A690
K
M
E
D
D
K
V
A
E
A
A
I
Q
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610719
1218
138870
N589
L
G
A
H
V
Q
S
N
L
Y
Y
N
T
V
K
Honey Bee
Apis mellifera
XP_623860
1203
137941
L574
A
D
T
I
S
M
V
L
K
K
L
G
Q
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790621
1624
181368
D753
V
C
K
N
I
N
L
D
H
E
S
H
L
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.3
88.4
N.A.
96.3
96.4
N.A.
94.4
91.4
84.4
63.9
N.A.
27.9
33.6
N.A.
40.3
Protein Similarity:
100
97.1
94.5
88.8
N.A.
97.7
97.7
N.A.
96.6
94.6
90.4
75.4
N.A.
46.5
52.3
N.A.
58.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
80
6.6
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
80
20
N.A.
33.3
0
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
8
0
8
8
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
70
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
8
8
70
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
70
0
8
0
0
0
0
8
0
0
70
0
0
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
8
0
77
0
% I
% Lys:
8
0
77
0
0
8
0
0
8
8
0
0
0
0
8
% K
% Leu:
77
0
0
0
70
0
8
8
8
54
8
0
77
0
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
8
70
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
70
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
8
16
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
70
8
0
8
62
0
0
8
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
70
% T
% Val:
8
0
0
0
8
0
16
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _